Effect of Using Vitamin C Supplementation on Performance, Blood Parameters, Carcass Characteristics and Meat Quality of Broiler Chickens Under Heat Stress Condition: A Meta-Analysis.
We explored how vitamin C supplementation affects cholesterol levels in broiler chickens, particularly under heat stress conditions. Through a thorough meta-analysis of 35 studies conducted between 1985 and 2023, we assessed various performance metrics, including blood parameters, carcass characteristics, and overall meat quality.
Our findings revealed that vitamin C significantly reduced cholesterol levels in the broiler chickens subjected to heat stress. Specifically, the study reported a notable decrease in cholesterol concentrations, with a standard mean difference of -0.976, indicating a strong beneficial effect of vitamin C in managing high cholesterol.
Additionally, we noticed improvements in body weight and average daily gain among chickens receiving vitamin C when compared to those that did not. While vitamin C did not significantly impact feed intake or breast meat quality, it emerged as a valuable antioxidant that can help lower blood triglycerides and reduce cholesterol, thus promoting better overall health and growth in broilers during stressful conditions.
Ultimately, this meta-analysis supports the use of vitamin C at a recommended dosage of 250 mg/kg as an effective growth promoter and antioxidant in broiler diets under heat stress, directly influencing cholesterol management.
Read More
9
Vitamin C's cholesterol-lowering potential
Vitamin C and E supplementation and high intensity interval training induced changes in lipid profile and haematological variables of young males.
To explore the impact of vitamin C on high cholesterol levels, we designed a study involving 106 young male athletes. They were divided into five groups, including those who did not exercise and those who underwent high-intensity interval training (HIIT), some with added vitamin C, vitamin E, or both. Over eight weeks, we assessed changes in lipid profiles and various blood variables.
Our findings were promising for those taking vitamins C and E alongside regular exercise. Participants who supplemented with these vitamins and engaged in HIIT showed significant drops in body weight, overall fat percentage, total cholesterol, and triglycerides. Remarkably, levels of high-density lipoprotein cholesterol, often dubbed "good cholesterol," increased in all four intervention groups. This suggests a potential role for vitamin C in improving cholesterol levels, especially when paired with an active lifestyle.
However, we also noted some adverse changes—specifically, reductions in certain blood cell counts among those only doing HIIT. While the vitamin-supplemented groups did experience effective elevation in beneficial vitamin levels, the overall effects of vitamin C alone on high cholesterol were less definitive, as the benefits appeared more in combination with exercise. It's safe to say that although vitamin C shows some promise in reducing cholesterol, the strongest benefits occur when it's part of a broader healthy regimen.
Read More
7
Vitamin C affects cholesterol interaction
Joint effects of paraoxonase 1 rs662 polymorphism and vitamins C/E intake on coronary artery disease severity (Gensini and SYNTAX scores) and lipid profile in patients undergoing coronary angiography.
This study aimed to explore how vitamin C intake interacts with a genetic factor known as the paraoxonase (PON) 1 rs662 polymorphism in relation to cholesterol levels. We analyzed data from 428 patients who underwent coronary angiography, focusing on their dietary habits and genetic backgrounds.
We found that individuals carrying the R allele of the polymorphism, especially those with lower vitamin C intake, were more likely to have elevated levels of low-density lipoprotein cholesterol (LDL-C). In fact, higher consumption of vitamin C was linked to a lower risk of high total cholesterol and LDL-C levels. Interestingly, those with the QQ genotype, who did not carry the R allele, did not experience the same level of cholesterol concerns associated with low vitamin C intake.
It’s important to note that while vitamin C appears beneficial in managing cholesterol for some individuals, the genetic factors need to be considered as they significantly influence the outcomes. Overall, our findings suggest that vitamin C can play a role in cholesterol management, particularly for those with specific genetic predispositions, highlighting the importance of personalized nutrition based on genetic makeup.
Read More
Most Useful Reviews
9
Supports cholesterol normalisation
3 people found this helpful
This vitamin C with quercetin is excellent! Quercetin aids in various conditions, including high cholesterol, insulin regulation, and inflammation. The effects are noticeable from the outset. I use it for allergies, viral infections, and managing diabetes, finding it particularly effective when combined with vitamin C and rutin.
Read More
7.5
Effective for cholesterol
17 people found this helpful
This product contains highly absorbable phytosome-processed quercetin and vitamin C, with an absorption rate 50 times greater than regular quercetin. Quercetin is vital for anti-aging but often poorly absorbed. For those seeking its benefits along with vitamin C, this product is ideal. I recommend it especially if there's a discount of 20% or more.
Read More
7.5
Expect cholesterol benefits
5 people found this helpful
It’s easier to drink than the vitamin C I previously took. With quercetin added to enhance absorption, I expect benefits in reducing total cholesterol, triglycerides, and blood sugar levels. I've bought two items and plan to continue with this for a while.
Effect of Using Vitamin C Supplementation on Performance, Blood Parameters, Carcass Characteristics and Meat Quality of Broiler Chickens Under Heat Stress Condition: A Meta-Analysis.
We explored how vitamin C supplementation affects cholesterol levels in broiler chickens, particularly under heat stress conditions. Through a thorough meta-analysis of 35 studies conducted between 1985 and 2023, we assessed various performance metrics, including blood parameters, carcass characteristics, and overall meat quality.
Our findings revealed that vitamin C significantly reduced cholesterol levels in the broiler chickens subjected to heat stress. Specifically, the study reported a notable decrease in cholesterol concentrations, with a standard mean difference of -0.976, indicating a strong beneficial effect of vitamin C in managing high cholesterol.
Additionally, we noticed improvements in body weight and average daily gain among chickens receiving vitamin C when compared to those that did not. While vitamin C did not significantly impact feed intake or breast meat quality, it emerged as a valuable antioxidant that can help lower blood triglycerides and reduce cholesterol, thus promoting better overall health and growth in broilers during stressful conditions.
Ultimately, this meta-analysis supports the use of vitamin C at a recommended dosage of 250 mg/kg as an effective growth promoter and antioxidant in broiler diets under heat stress, directly influencing cholesterol management.
Read More
9
Vitamin C and cholesterol benefits
Synchronizing positive effect of vitamin C and chromium on hyper lipidemia, hyperglycemia, liver enzymes and BMI of diabetes mellitus type 2 patients.
We conducted a study to explore how vitamin C, combined with chromium, affects high cholesterol levels in patients with type 2 diabetes. This interesting research involved 60 participants, evenly split between a treatment group receiving vitamin C (500mg) and chromium (200µg), and a control group taking a placebo.
Our analysis revealed notable reductions in several important lipid measurements within the treatment group. Specifically, we observed a significant drop in total cholesterol and improvements in High-Density Lipoprotein (HDL), Low-Density Lipoprotein (LDL), and triglyceride levels.
The results illuminate the potential benefits of vitamin C and chromium in managing cholesterol levels for those impacted by type 2 diabetes. While this study doesn't focus solely on vitamin C, the combined effects of both supplements indicate a promising avenue for improving lipid profiles and overall health in diabetic patients.
Read More
9
Vitamin C's cholesterol-lowering potential
Vitamin C and E supplementation and high intensity interval training induced changes in lipid profile and haematological variables of young males.
To explore the impact of vitamin C on high cholesterol levels, we designed a study involving 106 young male athletes. They were divided into five groups, including those who did not exercise and those who underwent high-intensity interval training (HIIT), some with added vitamin C, vitamin E, or both. Over eight weeks, we assessed changes in lipid profiles and various blood variables.
Our findings were promising for those taking vitamins C and E alongside regular exercise. Participants who supplemented with these vitamins and engaged in HIIT showed significant drops in body weight, overall fat percentage, total cholesterol, and triglycerides. Remarkably, levels of high-density lipoprotein cholesterol, often dubbed "good cholesterol," increased in all four intervention groups. This suggests a potential role for vitamin C in improving cholesterol levels, especially when paired with an active lifestyle.
However, we also noted some adverse changes—specifically, reductions in certain blood cell counts among those only doing HIIT. While the vitamin-supplemented groups did experience effective elevation in beneficial vitamin levels, the overall effects of vitamin C alone on high cholesterol were less definitive, as the benefits appeared more in combination with exercise. It's safe to say that although vitamin C shows some promise in reducing cholesterol, the strongest benefits occur when it's part of a broader healthy regimen.
Read More
7
Vitamin C lowers cholesterol in chickens
A comparative study on feeding timing and additive types of broilers in a high-temperature environment.
We observed how the timing of vitamin C (VC) supplementation could influence cholesterol levels in broiler chickens raised in a high-temperature environment. In our study, broiler chickens were given different treatments: some received VC from day one, while others only got it starting on day 22. Our findings indicated that the addition of VC from day one significantly lowered total cholesterol levels, compared to those who did not receive the supplement.
Furthermore, we noticed additional benefits with VC, including improved intestinal health and reduced stress indicators in the chickens. This suggests that early intervention with vitamin C could play a crucial role in managing cholesterol and overall well-being in chickens under heat stress.
Overall, our research highlights the potential of vitamin C as a dietary supplement to tackle high cholesterol in stressful conditions, providing a better understanding of its timing and effectiveness in poultry nutrition.
Read More
7
Vitamin C affects cholesterol interaction
Joint effects of paraoxonase 1 rs662 polymorphism and vitamins C/E intake on coronary artery disease severity (Gensini and SYNTAX scores) and lipid profile in patients undergoing coronary angiography.
This study aimed to explore how vitamin C intake interacts with a genetic factor known as the paraoxonase (PON) 1 rs662 polymorphism in relation to cholesterol levels. We analyzed data from 428 patients who underwent coronary angiography, focusing on their dietary habits and genetic backgrounds.
We found that individuals carrying the R allele of the polymorphism, especially those with lower vitamin C intake, were more likely to have elevated levels of low-density lipoprotein cholesterol (LDL-C). In fact, higher consumption of vitamin C was linked to a lower risk of high total cholesterol and LDL-C levels. Interestingly, those with the QQ genotype, who did not carry the R allele, did not experience the same level of cholesterol concerns associated with low vitamin C intake.
It’s important to note that while vitamin C appears beneficial in managing cholesterol for some individuals, the genetic factors need to be considered as they significantly influence the outcomes. Overall, our findings suggest that vitamin C can play a role in cholesterol management, particularly for those with specific genetic predispositions, highlighting the importance of personalized nutrition based on genetic makeup.
This vitamin C with quercetin is excellent! Quercetin aids in various conditions, including high cholesterol, insulin regulation, and inflammation. The effects are noticeable from the outset. I use it for allergies, viral infections, and managing diabetes, finding it particularly effective when combined with vitamin C and rutin.
Read More
7.5
Effective for cholesterol
17 people found this helpful
This product contains highly absorbable phytosome-processed quercetin and vitamin C, with an absorption rate 50 times greater than regular quercetin. Quercetin is vital for anti-aging but often poorly absorbed. For those seeking its benefits along with vitamin C, this product is ideal. I recommend it especially if there's a discount of 20% or more.
Read More
7.5
Expect cholesterol benefits
5 people found this helpful
It’s easier to drink than the vitamin C I previously took. With quercetin added to enhance absorption, I expect benefits in reducing total cholesterol, triglycerides, and blood sugar levels. I've bought two items and plan to continue with this for a while.
Read More
Frequently Asked Questions
High cholesterol, or hyperlipidemia, is a medical condition characterized by an elevated level of cholesterol in the bloodstream. Cholesterol is a waxy, fat-like substance that’s essential for building healthy cells, but too much of it can lead to serious health issues, including heart disease and stroke. Cholesterol is carried through the blood by lipoproteins, with two main types being low-density lipoprotein (LDL) and high-density lipoprotein (HDL). LDL, often referred to as "bad" cholesterol, can lead to the buildup of plaque in the arteries, while HDL, known as "good" cholesterol, helps carry cholesterol away from the arteries and back to the liver.
Factors contributing to high cholesterol can include poor diet, lack of exercise, obesity, smoking, and genetic predisposition. Regular health screenings are crucial, as high cholesterol often presents no overt symptoms. Maintaining a heart-healthy diet rich in fruits, vegetables, whole grains, and healthy fats, coupled with regular physical activity and avoiding tobacco, can help manage cholesterol levels effectively. In some cases, medications may be necessary to control high cholesterol, so consulting with a healthcare provider is key for tailored advice.
Vitamin C, also known as ascorbic acid, is a water-soluble vitamin that plays a critical role in numerous bodily functions. As an essential nutrient, it contributes to the growth and repair of tissues in the body, and it is vital for the production of collagen, an important protein that helps maintain skin, cartilage, tendons, ligaments, and blood vessels. Additionally, Vitamin C acts as a powerful antioxidant, which means it helps combat free radicals—unstable molecules that can cause oxidative stress and contribute to various chronic diseases.
Moreover, Vitamin C enhances iron absorption from plant-based foods, making it a vital component for those following vegetarian or vegan diets. While many people get sufficient Vitamin C from a well-balanced diet that includes fruits and vegetables like oranges, strawberries, kiwi, broccoli, and bell peppers, some individuals might require supplementation. It's generally recommended to stay within the daily intake guidelines, as excessive consumption can lead to gastrointestinal disturbances. Overall, Vitamin C is not just a skincare celebrity—it's a fundamental part of maintaining overall health and well-being.
Based on user reviews, individuals typically notice results from taking supplements for high cholesterol relatively quickly, often within the first few days to weeks. One user specifically mentioned that the effects of the supplement are noticeable from the outset, suggesting an immediate impact in their regimen for cholesterol management Read Review.
Another review pointed out the expectation of benefits in reducing total cholesterol and triglycerides, indicating a hope for changes reasonably soon after starting the supplement Read Review. However, experiences may vary depending on individual health conditions and diet, so monitoring progress over a few weeks is advisable for anyone looking to manage their cholesterol levels effectively.
Vitamin C demonstrates some potential in managing cholesterol levels, particularly when considered alongside other factors and in specific populations. For instance, a study involving patients with type 2 diabetes showed that vitamin C, when combined with chromium, led to significant reductions in total cholesterol and improvements in both LDL and HDL cholesterol levels [2]. This suggests that while vitamin C alone may not be the sole solution for high cholesterol, its combined effects can be beneficial in improving lipid profiles for those with underlying health conditions.
Additionally, research in poultry has indicated that vitamin C can effectively lower cholesterol levels in broiler chickens, especially when administered from an early age under stress conditions [1], [3]. However, in human studies, while vitamin C showed promise, especially when paired with lifestyle interventions like exercise, the results varied greatly based on genetic predispositions and overall health contexts [5]. Thus, while vitamin C might contribute positively to cholesterol management, it should be viewed as part of a broader approach that encompasses diet, exercise, and genetics.
Users have reported several improvements in symptoms when taking vitamin C combined with quercetin, particularly in managing conditions such as allergies, inflammation, and blood sugar levels. One user noted that the effects are noticeable right from the start, underscoring the immediate benefits of this combination for various health issues, including high cholesterol and diabetes management Read Review. They found the product effective not just for allergies but also as part of a broader health regimen.
In addition, users have expressed optimism about the potential for these supplements to influence key health markers. One individual specifically mentioned expectations for reductions in total cholesterol, triglycerides, and blood sugar levels due to the superior absorption of the phytosome-processed quercetin Read Review. Another user appreciated the combination of quercetin with vitamin C, suggesting a holistic approach to their health. Nonetheless, it's essential to remember that experiences can differ widely among individuals, and results may vary based on overall health, diet, and lifestyle.
Based on user reviews, there is a favorable sentiment surrounding the combination of vitamin C with quercetin for managing high cholesterol. Users report that quercetin not only supports cholesterol regulation but also provides benefits for conditions like diabetes and inflammation, with one reviewer highlighting the effectiveness of this combination right from the start Read Review. Moreover, the enhanced absorption of the phytosome-processed quercetin is mentioned as a significant advantage, potentially amplifying its cholesterol-lowering effects Read Review.
Additionally, users express optimism about the overall impact of combining these supplements, indicating expectations for reduced total cholesterol and triglycerides. One user specifically noted that the inclusion of quercetin along with vitamin C could lead to improved health markers Read Review. However, as with any supplemental approach, individual experiences may vary, and it's advisable to consider personal health conditions and dietary habits when evaluating these combinations.
Users report varying experiences with Vitamin C in conjunction with quercetin in their efforts to manage cholesterol levels. Many have noted that the combination is particularly effective, with one reviewer highlighting the ability of quercetin to aid in high cholesterol alongside its benefits in regulating insulin and inflammation Read Review. Others emphasize the enhanced absorption rates of this combination, suggesting that users seeking cholesterol reduction should consider products that optimize quercetin’s bioavailability, such as phytosome-processed formulas that are said to offer up to 50 times greater absorption compared to standard options Read Review.
In addition to the improved absorption, some users have expressed their expectations for these supplements to contribute positively to reducing total cholesterol and triglycerides alongside blood sugar levels Read Review. While specific dosage recommendations weren't mentioned in the reviews, the anecdotal evidence from users suggests that those looking to tackle high cholesterol may find success with a combination of quercetin and Vitamin C, particularly in formulations that boost absorption.
9
Supports cholesterol normalisation
3 people found this helpful
This vitamin C with quercetin is excellent! Quercetin aids in various conditions, including high cholesterol, insulin regulation, and inflammation. The effects are noticeable from the outset. I use it for allergies, viral infections, and managing diabetes, finding it particularly effective when combined with vitamin C and rutin.
7.5
Expect cholesterol benefits
5 people found this helpful
It’s easier to drink than the vitamin C I previously took. With quercetin added to enhance absorption, I expect benefits in reducing total cholesterol, triglycerides, and blood sugar levels. I've bought two items and plan to continue with this for a while.
7.5
Effective for cholesterol
17 people found this helpful
This product contains highly absorbable phytosome-processed quercetin and vitamin C, with an absorption rate 50 times greater than regular quercetin. Quercetin is vital for anti-aging but often poorly absorbed. For those seeking its benefits along with vitamin C, this product is ideal. I recommend it especially if there's a discount of 20% or more.
9
Vitamin C and cholesterol benefits
Synchronizing positive effect of vitamin C and chromium on hyper lipidemia, hyperglycemia, liver enzymes and BMI of diabetes mellitus type 2 patients.
We conducted a study to explore how vitamin C, combined with chromium, affects high cholesterol levels in patients with type 2 diabetes. This interesting research involved 60 participants, evenly split between a treatment group receiving vitamin C (500mg) and chromium (200µg), and a control group taking a placebo.
Our analysis revealed notable reductions in several important lipid measurements within the treatment group. Specifically, we observed a significant drop in total cholesterol and improvements in High-Density Lipoprotein (HDL), Low-Density Lipoprotein (LDL), and triglyceride levels.
The results illuminate the potential benefits of vitamin C and chromium in managing cholesterol levels for those impacted by type 2 diabetes. While this study doesn't focus solely on vitamin C, the combined effects of both supplements indicate a promising avenue for improving lipid profiles and overall health in diabetic patients.
9
Vitamin C reduces cholesterol levels
Effect of Using Vitamin C Supplementation on Performance, Blood Parameters, Carcass Characteristics and Meat Quality of Broiler Chickens Under Heat Stress Condition: A Meta-Analysis.
We explored how vitamin C supplementation affects cholesterol levels in broiler chickens, particularly under heat stress conditions. Through a thorough meta-analysis of 35 studies conducted between 1985 and 2023, we assessed various performance metrics, including blood parameters, carcass characteristics, and overall meat quality.
Our findings revealed that vitamin C significantly reduced cholesterol levels in the broiler chickens subjected to heat stress. Specifically, the study reported a notable decrease in cholesterol concentrations, with a standard mean difference of -0.976, indicating a strong beneficial effect of vitamin C in managing high cholesterol.
Additionally, we noticed improvements in body weight and average daily gain among chickens receiving vitamin C when compared to those that did not. While vitamin C did not significantly impact feed intake or breast meat quality, it emerged as a valuable antioxidant that can help lower blood triglycerides and reduce cholesterol, thus promoting better overall health and growth in broilers during stressful conditions.
Ultimately, this meta-analysis supports the use of vitamin C at a recommended dosage of 250 mg/kg as an effective growth promoter and antioxidant in broiler diets under heat stress, directly influencing cholesterol management.
7
Vitamin C lowers cholesterol in chickens
A comparative study on feeding timing and additive types of broilers in a high-temperature environment.
We observed how the timing of vitamin C (VC) supplementation could influence cholesterol levels in broiler chickens raised in a high-temperature environment. In our study, broiler chickens were given different treatments: some received VC from day one, while others only got it starting on day 22. Our findings indicated that the addition of VC from day one significantly lowered total cholesterol levels, compared to those who did not receive the supplement.
Furthermore, we noticed additional benefits with VC, including improved intestinal health and reduced stress indicators in the chickens. This suggests that early intervention with vitamin C could play a crucial role in managing cholesterol and overall well-being in chickens under heat stress.
Overall, our research highlights the potential of vitamin C as a dietary supplement to tackle high cholesterol in stressful conditions, providing a better understanding of its timing and effectiveness in poultry nutrition.
7
Vitamin C affects cholesterol interaction
Joint effects of paraoxonase 1 rs662 polymorphism and vitamins C/E intake on coronary artery disease severity (Gensini and SYNTAX scores) and lipid profile in patients undergoing coronary angiography.
This study aimed to explore how vitamin C intake interacts with a genetic factor known as the paraoxonase (PON) 1 rs662 polymorphism in relation to cholesterol levels. We analyzed data from 428 patients who underwent coronary angiography, focusing on their dietary habits and genetic backgrounds.
We found that individuals carrying the R allele of the polymorphism, especially those with lower vitamin C intake, were more likely to have elevated levels of low-density lipoprotein cholesterol (LDL-C). In fact, higher consumption of vitamin C was linked to a lower risk of high total cholesterol and LDL-C levels. Interestingly, those with the QQ genotype, who did not carry the R allele, did not experience the same level of cholesterol concerns associated with low vitamin C intake.
It’s important to note that while vitamin C appears beneficial in managing cholesterol for some individuals, the genetic factors need to be considered as they significantly influence the outcomes. Overall, our findings suggest that vitamin C can play a role in cholesterol management, particularly for those with specific genetic predispositions, highlighting the importance of personalized nutrition based on genetic makeup.
References
Tavakolinasab F, Hashemi M. Effect of Using Vitamin C Supplementation on Performance, Blood Parameters, Carcass Characteristics and Meat Quality of Broiler Chickens Under Heat Stress Condition: A Meta-Analysis. J Anim Physiol Anim Nutr (Berl). 2025. doi:10.1111/jpn.14091
Sabar N, Hussain MI, Saleem H, Khan MA, Khalid H, et al. Synchronizing positive effect of vitamin C and chromium on hyper lipidemia, hyperglycemia, liver enzymes and BMI of diabetes mellitus type 2 patients. Pak J Pharm Sci. 2024;37:199.
Son J, Lee WD, Kim H, Hong EC, Kim HJ, et al. A comparative study on feeding timing and additive types of broilers in a high-temperature environment. J Anim Sci. 2023;101. doi:10.1093/jas/skad290
Sarkar S, Dey SK, Datta G, Bandyopadhyay A. Vitamin C and E supplementation and high intensity interval training induced changes in lipid profile and haematological variables of young males. Sports Med Health Sci. 2023;5:137. doi:10.1016/j.smhs.2023.03.006
Darand M, Salehi-Abargouei A, Vahidi Mehrjardi MY, Feizi A, Seyedhossaini SM, et al. Joint effects of paraoxonase 1 rs662 polymorphism and vitamins C/E intake on coronary artery disease severity (Gensini and SYNTAX scores) and lipid profile in patients undergoing coronary angiography. Front Nutr. 2022;9:1097411. doi:10.3389/fnut.2022.1097411
Omidi S, Bouyeh M, Seidavi A. The effect of vitamin C and aspirin supplementation on the performance of turkeys under normal conditions. Anim Biotechnol. 2023;34:3395. doi:10.1080/10495398.2022.2152037